Sentence examples for many murine models from inspiring English sources

Th2 cytokines (IL-4, IL-5 and IL-13), which dominate many murine models of short term airway sensitisation, Th1cytokines (IFN-γ and IL-12), as well as IL-10, a cytokine associated with regulatory immune responses, were measured in BAL fluid by ELISA.

Th17 cells are central for the pathogenesis in many murine models of inflammatory diseases.

There are many murine models of autoimmunity that would be useful in exploring potential autoimmunity pathways.

Many murine models of type 2 diabetes, including mice with genetic modifications, fed with high-fat diet associated or not with low doses of STZ, extensively described an association between cardiac dysfunction and mitochondria alterations, including reduced ATP production, defects in mitochondrial respiration despite stimulation of biogenesis signalling and modified proteome [ 14- 16].

The protein was named Retn because in many murine obesity models, the circular level of Retn increases, inducing insulin resistance [ 2– 6].

The efficacy of LTβR pathway blockade (that is, the blocking of activation of LTβR by either of its ligands via the pharmacological inhibitor LTβR-immunoglobulin fusion protein [LTβR-Ig]) has been studied in many murine disease models (reviewed in [ 19]), and a human version was used in rheumatoid arthritis clinical trials [ 13].

Lymphopenia has been linked to autoimmunity in many different murine models and more circumstantially in patients [6], [7].

Unfortunately, knowledge regarding the role of NFκB during late embryonic development in general, and lung development specifically, has been limited by the embryonic and perinatal lethality observed in many of murine models containing deletions of NFκB family members (Table 1).

Taken together, observations from many studies on murine models imply that both androgens and estrogens are needed to induce proliferative, precancerous lesions and prostate cancer.

Many studies of murine models have found that effective DNA vaccination occurs in a dose-dependent manner, generally with a dose range of 25-200μg plasmiDNANA (1- 4).

Recently, many studies in murine models have shown that the depletion of T regs can amplify antitumour immunity (Viehl et al, 2006; Rudge et al, 2007).