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There are many mouse models for type 2 diabetes, Alzheimer's disease, stroke, cardiovascular diseases, osteoarthritis and osteoporosis12.
And now that the method is so fast, we can look at many mouse models," Kebschull says.
Many mouse models have been created to study hematopoietic cancer types.
There are already many mouse models of human diseases in which a simple genetic mutation in the mouse causes symptoms reminiscent of the human disorder.
This work has led to successful efficacy trials in many mouse models of neurodegenerative disorders including Alzheimer's, Huntington's, and Parkinson's diseases as well as spinal cord injury, traumatic brain injury, chemotherapy-induced neuropathy, ischemic stroke recovery, Rett syndrome, and epilepsy.
To understand the roles of Bcl-2 family protein in vivo, many mouse models have been developed.
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The relevance of IAP family proteins in vivo has been demonstrated by many mouse model studies.
Animal models, particularly mouse models, have been crucial to our understanding of immunology and immune tolerance, as evidenced by the many mouse model studies that are highlighted in this Review.
Many mouse DS models show reduced hippocampal LTP (Box 1).
This lack of evidence highlights again the uncertain relevance of many mouse disease models to the human conditions they may phenotypically resemble.
There are many known mouse models for motor neuron diseases.
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