Sentence examples for many molecular signalling from inspiring English sources

The advent of cell lines has allowed us to gain insight into many molecular signalling pathways; they are a useful tool to help develop novel therapeutic anticancer agents.

As many molecular signalling pathways are disrupted during lung carcinogenesis, we believe that combinations of biomarkers are necessary for precise diagnosis and prognosis of lung cancer, and thus we continue to search for superior biomarkers.

In low-temperature habitats (e.g., hydrothermal plumes, diffusing fluids, and chemosynthetic animal symbioses), many molecular signals and metabolic activities of aerobic methanotrophy have been observed.

Regardless of regulator loops and crosstalks in signaling networks, many molecular mediators transduce signals by means of PTMs which alter their functionalities (5, 6).

Ca2+ is a crucial point of intersection for many distinct molecular signaling pathways that promote and modulate angiogenesis.

Two unexpected discoveries, which are still the cause of some controversy, are that: (i) many molecular chaperones have intercellular signaling actions particularly with myeloid, lymphoid and vascular endothelial cells [26] and (ii) molecular chaperones can be found in the blood [27].

The existence of attractor selection in genome-encoded networks should be investigated in future studies, although the response of the whole genomic network in terms of attractor selection will be not as simple as that described here as it will involve combinations of many molecular mechanisms, including canonical signal transduction pathways.

Nevertheless, due to the many molecular levels regulating mTOR signal transduction, compounded by cell type specificity, the exact mechanisms of regulation and the impact of current therapeutics remain underdeveloped [ 40].

Many of the molecular signals and processes involved in fracture healing closely resemble those involved in bone development [ 9- 11].

Many of the molecular signaling pathways that are postulated to contribute to muscle atrophy in pre-clinical models mediate their effects through activation of the UPP [ 6].

At present, it is not definitely established as to how many types of molecular signals are involved and to what extent they modulate the transmission of irradiation effect.