Sentence examples for many molecular abnormalities from inspiring English sources

Many molecular abnormalities are identified in osteosarcomas giving the cancer cells some particular characteristics: proliferative signals (PDGFR, IGFR, c-KIT), resistance to retroaction signals (p53, RB), resistance to cell death (ERK, Bcl-2), angiogenesis (VEGFR, PDGFR), resistance to immune destruction (IFN) [ 12].

However, there remain many other molecular abnormalities in lung cancer that are as yet unexplored (Salgia and Skarin, 1998).

Further, it may be that more macroscopic markers and molecular markers need to be combined to be informative, as many individual molecular abnormalities in the brains of people with schizophrenia are often within the range of individuals without schizophrenia.

As for the HF-associated alterations in contractile function, many molecular HF-abnormalities have also been identified in HCM myectomy samples, suggesting that they are secondary to cardiac stress rather than primary causes of disease.

Remarkably, treatment with the anti-oxidant N-acetylcysteine (NAC) reversed many of the molecular abnormalities caused by Miner1 deletion.

Of interest, in each case, despite the complexity of aberrations revealed by NGS, many of the molecular abnormalities can be shown to converge, at least in part, on the PI3K/AKT/mTOR axis, perhaps accounting for the responses.

To date, there has been no study investigating the diagnostic and therapeutic potential of radiolabeled B-B4 mAb in breast carcinoma, particularly in TNBC cells such as the MDA-MB-468 cell line that shows many of the recurrent basal-like molecular abnormalities [20].

Many doctors would like to be able to detect molecular abnormalities directly on MRI machines, which provide crisp anatomical detail and don't involve radiation.

Molecular abnormalities commence in normal-appearing epithelium in chronically inflamed gallbladders.

Matching treatment to molecular abnormalities appears as a promising strategy.

Most cancers have multiple genetic alterations and molecular abnormalities.