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Many microorganisms are known to remain in favourable chemical environments and to disperse away from unfavourable environments.
Although the genome sequences of many microorganisms are now known, whole-genome DNA microarray platforms consisting of PCR amplicon, or oligonucleotide elements printed onto glass slides have been readily available for only a relatively few, highly studied microorganisms.
Many microorganisms are able to catabolize a plethora of aromatic compounds and interception of these pathways may lead to the biotechnological production of value-added aromatic compounds which will be discussed for Corynebacterium glutamicum.
Many microorganisms are found naturally in fresh and saltwater.
Many microorganisms are known to reduce chromium (VI) to chromium (III).
However, many microorganisms are unculturable, fastidious, or slow-growing.
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D-gluconate, an important carbon source for many microorganisms, is required for Escherichia coli (E. coli) to colonize the streptomycin-treated mouse large intestine (Sweeney et al., 1996), suggesting that gluconate might play an important role in both bacterial survival and virulence.
While many microorganisms have been shown to ferment glycerol, the fermentative metabolism of glycerol has been reported only in species of the genera Anaerobiospirillum [ 17], Bacillus [ 18], Citrobacter [ 18], Clostridium [ 19], Enterobacter [ 20], Escherichia [ 11], Klebsiella [ 21], Lactobacillus [ 18], and Propionibacterium [ 22].
Many microorganisms have been shown to limit the amount of accumulated 5-aminolenulevulenate [ 42], suggesting it may be particularly cytotoxic and/or the precursor to a rate-limiting step in tetrapyrrole biosynthesis.
With the development of metabolic engineering and synthetic biology, many microorganisms have been designed and modified for obtaining desired phenotypes.
Although many microorganisms have been used for the bioindustrial generation of valuable metabolites, the productive potential of cyanobacterial species has remained largely unexplored.
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