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4 5 Opponents dissent that the HSMR has too many methodological weaknesses and has not been well-validated as a useful measure.
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Five reviews of physiotherapeutic interventions show that there are few published studies on the effect of non-electrotherapeutic treatment, and many have methodological weaknesses.
Among these, many have methodological weaknesses such as the lack of comparison groups, and the outcomes examined were limited to vaccinations and nutritional status.
The more recent trials (Bowden et al. [2000]; Calabrese et al. [2003]; Bowden et al. [2003]; Weisler et al. [2011]) overcome many of the methodological weaknesses of the older trials of lithium that have been described in the past such as lack of intention-to-treat analysis, masking of treatment allocation, size, diagnosis, and discontinuation artifacts (Burgess et al. [2001]).
On the other hand, population-based, representative samples overcome many of these methodological weaknesses, while their findings allow inferences to be made to the general population [ 11, 13].
Meta-analytic evidence indicates that the relationship between risk appraisal and health behaviour is small, but studies examining this relationship have been criticised for their many conceptual and methodological weaknesses.
He pointed to a variety of methodological weaknesses (many of which have been addressed in subsequent papers by Jaeggi and others) and then presented the results from his own attempt to replicate the study, which found no effect whatsoever.
Digital manipulation of silhouettes can potentially be the best approach, yet previous studies of this sort embodied several serious methodological weaknesses: Many studies used schematic silhouette drawings developed by Singh (1993 ), which were extensively criticized for their poor realism and therefore unreliable results (Rilling et al., 2009 ; Tovée et al., 1999 ).
This may in part reflect the methodological weaknesses in many previous studies.
Several types of methodological weaknesses hamper many of the case control studies that have assessed the relative risk of psychoactive substance use for traffic injuries.
There have been numerous reports of associated risk factors for vertebral artery dissection; many of these reports suffer from methodological weaknesses, such as selection bias.
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