Finally, there were also many methodological differences across studies, including statistical models, study population characteristics (e.g., age and sex), use of lag days (e.g., a single lag and multiple lag), and potential confounders considered.
Spatial epidemiology of population-based case-control studies addresses many methodological criticisms of cluster studies and generates new exposure hypotheses.
Spatial epidemiology using individual level data from population-based studies addresses many methodological criticisms of cluster studies and generates new exposure hypotheses.
Because it is similar to our study in many methodological aspects, a recent study from Ireland [ 5] deserves more comments.
Apart from these study themes, Fergusson published many methodological aspects of longitudinal studies, especially those pertaining to measurement.
When available, population-based case-control studies provide extensive data on potential risk factors and residential histories that address many methodological criticisms of cluster studies.
When available, prospective cohort studies provide extensive data on potential risk factors and residential histories that address many methodological criticisms of cluster studies.
However, Cochrane's review suggested that these findings were inconsistent and highlighted many methodological concerns with previous studies [ 12].
Despite these positive outcomes, there were many methodological shortcomings in the studies reviewed, including insufficient information about randomization generation and absence of allocation concealment, lack of blinding and no placebo control, absence of intention-to-treat analysis and lack of follow-ups, selective publishing and reporting, and small number of sample sizes.
There are many methodological differences between the study of Zagli et al. and our study, but both showed that the sensitivity of LUS/PCT is superior to other diagnostic approach based on CXR in the diagnosis of pneumonia.
