Sentence examples for many mast cells from inspiring English sources

Systemic mastocytosis is a rare disease in which the body accumulates too many mast cells.

Although researchers know the functions of many mast cells in the body, a subset that inhabits the brain has remained mysterious.

However, the depleted animals that had been injected with ArtinM had 3 times as many mast cells (1.53±0.1%) as the depleted animals that had not received the lectin and in the animals injected with ConA the percentage was only 1.18±0.2% (Fig. 10).

This might, thus be interpreted as that many mast cells is an additive favourable prognostic sign even though it was not an independent prognostic marker in this study.

In Hodgkin lymphomas, many eosinophils in the tumours are correlated to an unfavourable prognosis [ 7] and many mast cells have been associated with an adverse clinical outcome [ 21].

This is confirmed by the finding of Nielsen et al [ 17], who used the same tryptase antibody as we did and also found a positive influence of many mast cells on prognosis.

It is now well-established, for example, that fibroblasts play a pivotal role in promoting the growth of many types of cancer cells [ 7- 9] and that many mast cell granule components exert powerful effects on fibroblasts [ 2, 10].

We have previously shown that the CF mouse has many more mast cells in the small intestine as compared to wild type (WT) mice [17].

In many diseases mast cells re-locate to specific compartments within tissue, such as the airway smooth muscle 10 and submucosal glands 11 in asthma.

The finding of many stromal mast cells close to microvessel and the association to microvessel density might be explained by contribution of mast cells to neo-angiogenesis in these tumours.

A bone marrow biopsy at the time of diagnosis showed multiple paratrabecular and perivascular mast cell aggregates comprising 30 50% of the marrow space, as well as many fusiform mast cells.