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This gives Schlessinger's map three times as many markers as the previous chromosome X map.
The downside of studying a group of SNPs is that the method sometimes identifies too many markers as CNNLOH, which affects specificity negatively (see Fig. 5B).
These scripts require a data file, markerphyspos.txt in the example files, which contains genetic positions for each marker (and/or interpolated marker if interval mapping has been performed) in the R/qtl output file as well as physical positions for as many markers as possible.
It is also why we need as many markers as possible for any given cell type.
When we used as many markers as possible, however, we could achieve a good reconstruction of the species history.
For each marker, Blossoc considers the region around that marker that includes as many markers as possible without violation of the four-gamete rule.
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As expected, this extensive list includes many astroglial markers such as vimentin, S100β, aquaporin 4 and aldehyde dehydrogenase 1 family, member L1 (AL1h1L1) [23].
For example, many metabolic markers, as well as certain hormones such as insulin, change in concentration after food consumption.
In order to incorporate as many markers of different types as possible, a reduced population size was employed with marker redundancy kept as low as possible.
It can also explain the lack of association with as many markers in the multivariate analysis in our population.
A lower LOD was selected when a single marker dropped out of the linkage group at LOD 4.0, in order to maintain as many markers in the analysis as possible.
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