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Many mRNAs encoding for these proteins are found in the cortex (α5 and β3) and in the hippocampus (mainly α5).
Puf3p is also known to bind to a consensus motif in the 3'UTR of many mRNAs encoding mitochondrial proteins [16] [16].
Many mRNAs encoding glycolytic and TCA cycle enzymes exhibited a characteristic expression pattern.
These findings indicate that NF90 collectively associates with many mRNAs encoding SASP factors in human fibroblasts.
Syp associates with multiple transcripts encoding key synaptic regulators, as well as many mRNAs encoding proteins of unknown function.
UUA codons are found in many mRNAs encoding proteins involved in the regulation of antibiotic synthesis and cell development [53].
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Many of the mRNAs encoding the previously mentioned genes contain 5' un translated regions which are G+C rich and difficult to translate and referred to as weak mRNAs [ 35]. 4EP-B1 forms a complex with these mRNAs and other binding factors allowing the translation of these weak mRNAs [ 35, 53- 58].
We also observed reduced levels of mRNAs encoding many of the energy-related proteins up-regulated in the rapidly growing Day-6 population.
The mRNAs encoding many of the glycosomal enzymes are known to be more abundant in bloodstream forms than in procyclics, and there is less PYK mRNA in short stumpy forms than in long slender trypomastigotes [ 1].
Since mRNAs encoding many different proteins were reduced in amount in CP-r cells, we sought to determine whether DNA hypermethylation might account for decreased transcription of certain genes in CP-r cells.
However, his mechanism is not supported by gene expression profiling experiments in S2 cells [ 31], which show that TOR regulates many genes involved in ribosome assembly, but does not affect the expression of mRNAs encoding the ribosomal proteins.
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