The Intel Xeon Phi co-processor, built upon the MIC architecture, features many low frequency, energy efficient cores.
Aphid populations are sometimes composed of a small number of dominant genotypes ("clones") and many low frequency (rare) genotypes [42], [49], [50], [51], [52].
Thus, for the GWLS samples examined, the genetic architecture suggested for both disorders is one dominated by heterogeneous models, via the involvement of many low frequency or rare loci, each relevant to a subset of affected families.
First, how many low frequency and rare variant associations can we reasonably expect to identify and in what sample sizes?
Many low frequency SNPs that were identified through sequencing of individual DNA samples were missed in the sequencing of pooled templates.
Finally, in performing multiple repetitions of sequencing reactions, we observed that many low frequency sequences were only present in one or a few sequencing reactions.
Clearly, a small threshold allows wavelet denoising to preserve more details from the raw spectrum, but it keeps many low frequency noises in the denoised result, which will turn into false-positive peaks in detection.
The last 'two step approach' uses a local reference panel consisting of a subset of samples with a chip containing many low frequency variants or local sequencing data [ 18, 19].
Through the Fast Fourier Transform (FFT), Fig. 6 gives the results of spectrum analysis of response and sinusoidal waves, which demonstrates many low-frequency waves in the response spectrum.
