Sentence examples for many loci which from inspiring English sources
Interestingly, our data show that long-term depletion of both DNMT1 and DNMT3B, as observed in DKO cells, may overcome demethylation-resistance at many loci which supports the development of specific and non-toxic inhibitors for clinical improvement of epigenetic therapy.
With such genomic features, evidence is gathered at many loci, which make the findings not heavily dependent on specific loci in individual samples.
This included disqualifying reads that mapped to too many loci, which may represent a repetitive region, or gene fusion candidates which mapped to two homologs that were part of the same gene family.
The reason for this is that in the natural strains, trade-off was mitigated over time by passing on fitness costs to many loci, which become visible when they become unlinked in the cross.
Ciofani et al. (2012) showed that BATF and IRF4 have common putative cis-regulatory modules (pCRMs) and function together in many loci, which include the most pCRMs for STAT3 and RORγt found in Il17a, Il17f, Il12b1, Il1r1 and Rorc loci.
Since it is known that the variance of the distribution for expression level across samples tends to exceed the mean of the distribution at considerably many loci, which is called overdispersion, and the negative binomial distribution fits to the data better than Poisson [ 18], the edgeR package is widely used.
However, the other studies have reported many different loci, which is likely a reflection of the genetic heterogeneity of migraine.
Although cross-amplification often failed in samples from the eight related taxa, there were many loci at which amplification was successful (Appendix 1, Table 3).
This included many loci for which crop alleles were in excess of expectations for band present states of both L. sativa and L. serriola.
There are many loci at which di-cistronic read-through transcripts are evident (Pelechano et al., 2013), raising the possibility that transcriptional interference leading to reciprocal expression of genes in tandem arrays is a much more widespread phenomenon in yeast.
A closer inspection of the genotype data in GenomeStudio (Illumina) revealed low cluster separation calls for all SNPs and a number of different causes for the discrepancies in these data, including many loci for which data were grouped into more than one sub-cluster in each genotype.
