Sentence examples for many loci implicated from inspiring English sources

Motivation: Genome-wide association studies (GWAS) have identified many loci implicated in disease susceptibility.

The central, or class III, region of the major histocompatibility complex (MHC) is an important gene rich sub-region of the MHC of mammals and contains many loci implicated in disease processes and potential productivity traits.

For many of the loci implicated in metabolic disease, such as the ones flagged in GWAS, it is not always clear which underlying variant or gene is involved (27, 28).

Most loci are in relation with the CD phenotype and many loci are implicated in other immune-mediated disorders, most notably with ankylosing spondylitis, erythema nodosum, and psoriasis [ 28].

In this respect, the association of rs5848 with FTLD-U is similar to many other neurodegenerative diseases where genetic variability at the same loci implicated in Mendelian pathogenic forms of the disease predispose to sporadic forms of the disease (24– 24).

The majority of loci implicated to affect sleep in our analysis of natural variants are novel, many are in non-coding, intergenic regions, and several SNPs could potentially affect more than one gene.

Histone-enriched regions include several loci implicated in embryonic development.

Particularly over-represented are loci implicated in T-helper-cell differentiation.

The GCKR locus is the strongest completely novel locus implicated in TG metabolism [ 12].

Our data map the primary contribution of oxidative demethylation to a subset of gene bodies and intergenic sequences and implicate redundant pathways at many loci.

Although many genetic loci are implicated in Crohn's disease, few have been associated with post-resection recurrence.