Sentence examples for many known substrates from inspiring English sources

While the high-ranking Akt, mTORC1, and PKA predictions from our machine learning approach included many known substrates for each kinase, there were also many phosphorylation sites not previously recognized as part of the insulin signaling network.

DPP4 has currently many known substrates (see Table 1).

This restraint reflects the observation that many known Cdk substrates contain multiple clustered phosphorylation sites.

To uncover the underlying molecular mechanism, we examined the changes in many known FBW7 substrates, such as cyclin E, c-Myc, c-Jun, Notch-1, SREBP1, PGC-1α, KLF-5 and Mcl-1.

However, many MATE transporters do not have known substrates, and MATE transporters are even found in antibiotic hypersensitive strains [ 52].

However many, like Fbxl7, are still uncharacterized as 'orphan' F-box proteins with no known substrates.

Among many others, p27, c-Myc, E47, and Tal1/Scl (T cell acute leukemia 1/stem cell leukemia) are well known substrates of SCFSkp2 [ 94– 94].

Many of these expansions are for predicted hydrolases, phosphatases in particular, but their substrate specificities are either unknown or the affinity of known substrates is extremely low [47].

It has no known substrates.

All drugs found to interact with MsbA in this study are known substrates of other MDR transporters, such as Pgp and LmrA, which recognize and transport a plethora of chemical species, many of which are positively charged.

Proteome signatures that are hallmarks of proteolysis revealed cleavage of many known MMP-2 substrates in the cellular context.