Sentence examples for many key regulators from inspiring English sources

In recent years, many key regulators and their downstream genes participating in the regulation of trichome formation have been identified.

Mammalian iron metabolism is tightly regulated (Wang and Pantopoulos, 2011) and involves, among many key regulators, Tf (transferrin) and TfRc1 (Tf receptor) 1 and TfRc2 (Dautry-Varsat, 1986; Anderson and Vulpe, 2009).

Here, we review the contributions of the molecular chaperone Hsp90, a protein that facilitates the folding of many key regulators of growth and development, to canalization of phenotype - and de-canalization in times of stress - drawing on studies in eukaryotes as diverse as baker's yeast, mouse ear cress, and blind Mexican cavefish.

For instance, many key regulators need only be active transiently to achieve permanent reprogramming [7].

We have previously shown that many key regulators of the caspase-dependent cell death signaling cascade are abundant in the embryonic heart but their expression is downregulated during development and these proteins are not re-expressed during experimental ischemia or ischemia-reoxygenation in vitro [2].

For both adipogenesis and osteoblastogenesis, many key regulators have been identified using established cell model systems.

Besides, several studies also revealed that interphase components might be used to regulate mitosis, and many mitotic key regulators also have important functions during interphase.

It is also responsible for the proteolytic maturation of diverse polypeptide precursors and for the spatial and temporal regulation of the degradation of many key cell regulators whose destruction is necessary for progression through essential processes, such as cell division, differentiation and, more generally, adaptation to environmental signals.

Previous studies have revealed that GATA was active in transcriptional regulation in human ES cells through transcriptional coexpression with many other key regulators [ 25, 27, 28].

Similar to Drosophila blastoderm nuclei, the pluripotent properties of human embryonic stem cells are reflected by the presence of paused Pol II complexes on a wide number of genes, including many key developmental regulators [2].

Equally, in our data we find that many key muscle regulators have low to moderate expression, including MSTN.