Sentence examples for many key pathways from inspiring English sources

To address these limitations, an international task force of 180 scientists was assembled to explore the concept of a low-toxicity "broad-spectrum" therapeutic approach that could simultaneously target many key pathways and mechanisms.

However, the available results clearly point to a general involvement in the control of many key pathways that impinge on the regulation of gene expression [ 4].

Several hurdles still need to be overcome, including improved compound specificity and the importance of many key pathways for homeostasis and host defense [ 37].

Endospore formation distinguished Lachnospiraceae from different habitats, with complete or near-complete sporulation pathways in human gut-associated microorganisms, and many key pathways absent from other members of the group.

p53 interacts with mammalian target of rapamycin (mTOR) and AMP-activated protein kinase (AMPK), two master regulators of cellular metabolism, directly influences many key pathways involved in carbohydrate and lipid metabolism, and regulates autophagy and the oxidative stress response.

Functional analysis revealed that many key cellular pathways in human bone marrow MSC self-renewal, such as the canonical signaling pathways, cell cycle pathways and cytokine related pathways may be regulated by H3-Lys9 modifications.

These results indicate that in response to THZ treatment, a significant lowering of the expression of genes belonging to many key biosynthetic pathways is observed.

Mitochondria are critical cellular organelles in which many key metabolic pathways converge.

Without these proteins, many key metabolic pathways of C. jejuni would cease to function (Miller et al. 2009).

P is involved in the regulation of many key metabolic pathways in all living organisms, including energy generation, nucleic acid and membrane synthesis, protein phosphorylation and redox reactions [ 1– 3].

Increased HLs after RP and decreased relative protein abundance in many key metabolic pathways in old mice, coupled with increased polysome loading (most likely due to a reduction in elongation rate), suggest a slowing of protein synthesis with production of higher quality, longer lived proteins after RP.