Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
In addition, isoform-based approaches increase the complexity of studying splicing regulation when many isoforms are present in the sample.
Similar(59)
Next, we verified how many isoforms were simultaneously co-expressed in the different samples.
Given the results of Cao et al.'s study and the fact that many isoforms were also stained during RAET1E and RAET1G IHC staining, it is possible that high RAET1E and RAET1G expression may be associated with poor prognosis.
Next, to validate VMN vs. H tissue comparisons with qPCR, we chose nine functionally important candidate genes that were upregulated in the VMN (Additional file 1: Table S6), regardless of how many isoforms were predicted by Trinity.
Many alternative isoforms are expressed in a spatio-temporal manner, and function in diverse processes, including in the neural system.
Many Rab7 isoforms are also present in plant taxa.
How many protein isoforms are detected that fulfil the 2 peptide criteria?
This indicates that many splicing isoforms are only expressed in a small number of HeLa S3 cells.
These studies confirmed that many H2B isoforms are present at the protein level for the first time but failed to detect some lower abundance H2B isoforms.
Most prominent were TRPM7 and M3 and TRPC3 and C4, but many other isoforms are potentially relevant as their transcripts occurred at significant levels.
Although more isoforms can be discovered (thus improving the sensitivity), many incorrect isoforms are also predicted (thus hurting the precision) because of the increased difficulty in dealing with complex splicing patterns.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com