Sentence examples for many interaction partners from inspiring English sources
Some researchers have sought to refine the notion of centrality by considering interaction patterns of central nodes: those that interact with many interaction partners simultaneously are called "party" hubs whilst those that interact with a few of their partners at a time are called "date" hubs [ 128].
This measure allows us to observe a decreasing trend of s(k) with k (Fig. 3b) as a power-law, suggesting that domains with many interaction partners only occasionally interact with each partner.
L2-PPI scores are imputed in edges whose proteins do not actually interact according to PPI databases, yet who share many interaction partners.
We chose 14 SYNZIPs for in vitro testing, selecting proteins that had many interaction partners in the prior coiled-coil microarray tests or that interacted with a SYNZIP that had many interaction partners.
Trx-1 has many interaction partners depending on its cellular localization.
It is likely that for popular genes with many interaction partners, not all interactions are of equal relevance.
However, a protein with many transient interaction partners may transiently interact with its different partners through the same binding interface (though it is possible that the protein may form a transient complex with its partners through multiple distinct binding interfaces), thus the PPID of the protein may not well reflect the proportion of its interface residues [ 22].
Utilizing the combined information of the co-occurrence network and the physical interaction network, we also find that domains tend to interact infrequently if they have many different interaction partners.
DISC1 encodes a cytoplasmic protein with many potential interaction partners, but its cellular functions remain poorly understood.
In many cases, interaction partners for individual SH3 domains have been identified, e.g. by pull down assays.
In addition, with STAT3 mediated leptin signalling, we only tested one of the many potential interaction partners of SH2B1 in regulation of energy homeostasis.
