Sentence examples for many interacting pathways from inspiring English sources

ER levels are controlled in a homeostatic fashion by many interacting pathways.

However, despite the identification of many interacting pathways [4], it remains unclear how the highly variable, context-specific effects of Notch signaling are integrated at the molecular level, i.e. which specific target gene programs are activated.

Many interacted pathways play a role in T2D genetic risks, which includes insulin signalling pathway, type II diabetes pathway, maturity onset diabetes of the young, adipocytokine signalling pathway, and pathways in cancer.

For example, salinity, drought, and cold elicit a dehydration response that shares many common elements and interacting pathways [ 6, 7].

Clearly, many of these SNPs are not only in linkage disequilibrium but also the genes studied are part of interacting pathways.

Meanwhile, inflammation has been proposed to be a critical promoter of atherosclerosis, interacting with many pathophysiologic pathways to lead to vascular stiffness.

To our current knowledge, c-Jun remains at the centre stage of a complex molecular network, c-Jun interacting with many signalling pathways, some of which are yet to be discovered.

Consistent with its pleiotropic role, leptin interacts with many signalling pathways including those involving NO [64].

Siah proteins can interact with many intracellular pathways, including the scaffold proteins, transcriptional repressors and nuclear receptor corepressors and β-catenin.

The tumor microenvironment can have a profound influence on cellular behavior, and hypoxia has been shown to interact with many oncogenic signaling pathways.

NR2F2 generally is thought to functionally interact with many different signaling pathways such as Notch, β-catenin, transforming growth factor-β (TGFβ), HNF4α, runt related transcription factor (Runx 2, PPARγ, CCAAT/enhancer binding protein (C/EBP) α, GATA, RARα or PPARα pathways [ 34, 39- 48].