Sentence examples for many inflammatory pathways from inspiring English sources

It is important to mention that, in sepsis, many inflammatory pathways are activated in parallel with a reduction in the PI3K/Akt pathway, thus, merely blocking a single component of the inflammatory pathways or inducing the activation of PI3K may be insufficient to arrest the process.

Tumour necrosis factor-alpha (TNFα) is a key and proximal component of many inflammatory pathways.

Pete Nelson (FHCRC) discussed how DNA damaging therapeutics led to profound increases in many inflammatory pathways in the prostate.

Obesity activates many inflammatory pathways that deregulate physiological responses, which maintain metabolic homeostasis including insulin and leptin sensitivity.

Because many inflammatory pathways are triggered in sepsis, merely blocking a single component is likely to be insufficient to halt the process [ 45, 46].

The role of SHIP-1 is essential for the suppressor activity of macrophages and is a potent inhibitor of many inflammatory pathways [ 24, 25].

Ligand binding to TLR9 results in the recruitment of adaptor proteins, MyD88, to ultimately lead to the activation of NF-κB, a key regulator of many inflammatory response pathways [8].

Here we have examined many potential inflammatory pathways that might explain this exacerbation of disease, including transcription of iNOS and matrix metalloproteinases such as MMP9, the induction of IFNγ and TNF-α and increased infiltration of cytotoxic T cells or natural killer cells.

Many inflammatory intercellular signal pathways, such as NF- κB, MAPK pathways, and Jak-Stat3 pathway, are involved in the activation of RASFs.

Many inflammatory mediators or pathways are known to possess two-sided Janus faces.

They demonstrated that many inflammatory genes and pathways were shared across RA and SpA.