Sentence examples for many human solid from inspiring English sources

QR1's ability to bioactivate quinones and its elevated expression in many human solid tumors makes this protein an excellent target for enzyme-directed drug development.

Because NQO1 is expressed at high levels throughout many human solid tumors, compounds efficiently bioactivated by NQO1 have been designed for the therapy of tumors rich in NQO1.

NAD(P H: quinone oxidoreductase 1 (NQO1) is an obligate two-electron reductase and is highly expressed in many human solid cancers.

Moreover, it inhibited the growth of many human solid tumor xenografts in a dose-dependent way range 50 100 mg/kg).

Ras-association domain family 1 (RASSF1) was discovered as a tumor suppressor gene located on human chromosome 3p21 in a segment that is deleted in many human solid tumors [9].

RASSF1A is a tumor suppressor gene which is epigenetically inactivated by cytidine methylation in many human solid tumors.

Nucleophosmin is overexpressed in many types of human solid tumors.

However, many human diseases (including solid tumors) are driven by persistently up-regulated angiogenesis [ 1].

The enhanced permeability and retention effect has been observed in many experimental and human solid tumours (Maeda et al, 2000).

The MLL3 gene, for example, is frequently mutated in many types of human solid tumors, including breast cancer, approximately 40% of which show reduced MLL3 protein expression [107].

Overall clinical response rates to EGFR targeted therapy in many of the common human solid tumours are generally low, often in the range of 5 20% (Castro, 2002; Fukuoka et al, 2003; Kris et al, 2003).