Sentence examples for many histone modifications from inspiring English sources

Many histone modifications, including acetylation, phosphorylation, ubiquitination, sumoylation, and methylation, are known to regulate chromatin structure and gene expression [1], [2].

Many histone modifications have been reported to be highly related with gene transcription.

Many histone modifications are stable or only partially diminished throughout mitosis.

In mammals, many histone modifications and other chromatin changes cooperate to establish and maintain the silent state.

On the other hand, many histone modifications are diffuse and occupy large regions, ranging from thousands to several millions of base pairs.

Whereas correlations between many histone modifications and various chromatin states are well established, the function of these marks is an area of continued debate.

Many histone modification enzymes are recruited to enhancers by transcription factors.

However, we did not find many identical histone modifications in adipocytes from six different individuals.

H4R3 methylation by PRMT1 in vivo is required for many subsequent histone modifications in mammalian cells [ 30].

While the function of many active histone modifications is not fully understood, there is abundant evidence that their deposition is required for the proper regulation of gene expression.

Many mono-methylated histones, as well as H3K4me2-3 and H3K79me3, are associated with a similar set of TSS regions (Additional file 4: Figure S3A and Additional file 5: Table S4), consistent with the fact that many such histone modifications are associated with active transcription [ 15].