Many genotypes were examined in this data set, but Bonferroni correction for all combinations seems overly stringent [ 13].
Many genotypes were missing, mainly for controls because of difficulties in extracting DNA from hair samples (n = 117) and for a few cases because of unsuitable samples (n = 13).
We reviewed previously reported emm 1, 12, and 66 superantigen genotypes and found many genotypes have been given multiple names.
Many common genotypes are broadly distributed and it is not possible to estimate the relative frequency of genotypes in different host reservoirs accurately.
Human papillomaviruses (HPVs) are small double-stranded DNA tumor viruses infecting oral mucosa and genital tracts; many HPV genotypes are found in both these localizations.
This is intermediate between using a raw p value (least conservative) and Bonferroni correction (most conservative), and accounts for the fact that many of the genotypes are in partial LD and, thus, many of the hypothesis tests are correlated.
Under field conditions, the result would be a segregation pattern that is systematically different from neutral expectations in progeny as many, less fit, genotypes are purged from populations (Burke and Arnold 2001).
Many G. barbadense genotypes are known to carry high levels of resistance to VW [ 6– 8], but its resistance has not been successfully transferred into commercial Upland cotton due to hybrid breakdown except for introgressed breeding lines [ 7, 9].
In many locations genotypes were observed that were either homozygous for the reference sequence or heterozygous, but the variant homozygous genotype was not observed.
It is also not clear how many genotypes might be competing at any given time, which is an important parameter for studying properties of adaptation and predicting adaptive walks.
