Sentence examples for many genetic polymorphisms from inspiring English sources

Genetic background means that the genome of the house mouse contains many genetic polymorphisms causing variations in brain development and in behavioral performance.

As allele frequency for many genetic polymorphisms differs based on racial and ethnic background, this leads to questions about differences in brain structure or function based on ancestry.

These include P2X7 expression and function vary between tissues and with species [33], human P2X7 exists in at least 7 different spliced forms [36], and there are many genetic polymorphisms [37].

Many genetic polymorphisms influence phenotype by altering the level of expression of their respective proteins; some authorities feel that these expression-level polymorphisms are more significant – on a population-wide basis – than are polymorphisms that directly impact protein structure or function [21] [29].

Moreover, many genetic polymorphisms were reported to affect the disposition of olanzapine and clozapine.

Links have been established between many genetic polymorphisms and risk for severe sepsis and CAP.

Since the discovery of differences in extent of excretion of isoniazid, a vast literature has developed documenting many other genetic polymorphisms for drug metabolizing enzymes and drug transporters.

Age is the most common risk factor for its initiation and progression, with symptomatic OA affecting 10 to 20% of people more than 50 years old [ 2]. 'Wear and tear' injuries due to mechanical loading over many years, genetic polymorphisms and other factors contribute to the development of the disease.

Many of these genetic polymorphisms are known to have clinical effects and to exhibit interethnic differences (Table 1 ).

102 The biological explanations for these sex differences are not fully understood, in part because the physiological effects of many of the genetic polymorphisms have not been completely determined.

The levels of IL18 are influenced by many factors of which genetic polymorphisms may contribute.