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Exact(13)
However, for many genetic mutations, the presence of the identical mutation is associated with marked phenotypic range that affects muscle function as well as cardiac function.
Even though many genetic mutations are present in tumor cells, Califano has shown that these mutations converge to and are integrated by specific proteins called master regulators, which activate the programs that are necessary to make a cancer cell.
When a new protein evolves in nature, the process usually requires many genetic mutations that are acquired over many generations.
Researchers proposed that HSP90 allows the flies to store many genetic mutations in normal times but express them only in tough times.
It's well-accepted that a new species will arise when a subset of an existing species breaks off and accumulates too many genetic mutations to breed with members of the original species.
Compared with healthy cells, cancer cells contain many genetic mutations.
Similar(47)
This major new study which is prompting gleeful headlines around the world actually tells us that there is no common genetic cause of autism, that there are many specific genetic mutations involved with autism.
Doctors unconnected with Vertex give use a more muted word to describe the new drug, tezacaftor: incremental, a small step along the path of coming up with a treatment for all the patients with the many different genetic mutations that can cause cystic fibrosis.
After revealing extremely high incidence of mutations in solid cancer (Table 1), very little scientific rationale has been presented for developing such costly molecular target drugs that are based on identification of too many evolving genetic mutations in the chaotic cancer environments.
Given the ease of this novel approach, it should be possible in the future, to test many known genetic mutations or well defined inhibitors, e.g. of signaling pathways or key enzyme systems, for their impact on central PMN functions.
But many hereditary genetic mutations and somatic mutations do not result in cancer, presumably because additional actions (e.g. sustained proliferative signaling) are needed or additional biological safeguards still need to be suppressed or defeated (e.g. apoptosis, senescence, immuno-surveillance and so on) before a fully immortalized cellular phenotype can emerge.
More suggestions(15)
many genetic features
many genetic changes
many different mutations
many genetic oscillators
many beneficial mutations
many such mutations
many genetic diseases
many genetic variants
many genetic markers
many genetic conditions
many serious mutations
many possible mutations
many genetic operators
many genetic alterations
many genetic resources
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com