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For example, how is the expression of so many genes regulated by limited cohorts of regulators and how are genes differentially expressed in different tissues despite the genetic code being the same in all tissues?
Many genes regulated by the Notch pathway were expressed in effector cells, but not in memory T cells.
Many genes regulated by cisplatin belong to two main groups: cell cycle and proliferation.
Similarly, many genes regulated by GEMM RNA motifs can be assigned to cellular motility, virulence and biofilm formation.
These findings indicate that histone acetylation and phosphorylation may profoundly affect the expression of many genes regulated by the bivalent chromatin methylation marks in hPSCs.
16, 17 Transcription of many genes regulated by OCT4, SOX2, and Nanog could be controlled by transforming growth factor-β/SMADs.
Similar(44)
Our data suggest that the impact of P4 on cholesterol metabolism is profound and involves broad transcriptional regulation of many genes regulating cholesterol and lipid biosynthesis and transport.
We found that many genes regulate the genome-wide mRNA expression through regulatory networks of intragenic L1s.
Besides other causes, these diseases have complex genetic component which involves many genes regulating the extent of immune response.
By comparing gene expression in tumors of differing metastatic ability we found that many genes regulating motility and invasion are dramatically changed in metastatic cells.
Interestingly many genes regulating programmed cell death were also found in GISTIC peaks (BCL2, BCL-XL, PDCD1, CRK), suggesting an important role of apoptosis in TET pathogenesis.
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