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Thus, the highly precise positioning of the polyadenylation in Blastocystis has allowed reduction of the 3′-untranslated regions to the point that, in many genes, only one or two nucleotides of the termination codon are left.
Our protocol has already clustered alternative splicing products to their closest counterparts however the majority of proteins in the dataset are inferred from predicted gene annotations and for many genes, only one protein product is predicted.
1) There is still considerable variation in expression levels between the different genes and tissues in our study, with many genes only expressed in one or a few tissues.
Because RpoS also has a small effect on LasR and RhlR expression [ 15], it appears that RpoS is capable of advancing many genes only indirectly through LasR and RhlR.
Second, the coverage in our samples (even the new replicates) is low enough that many genes only have a small handful of footprints, so we'd be comparing a lot of sites with few or no reads (i.e., the variability is not informative).
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The selection of filter function and scaling level for wavelet transform, as well as the validation of the method, is discussed in detail in Additional File 1. CNV regions harbor many genes but only a small portion of them are cancer causal genes.
Austin has been studying the value of genetic counseling for patients with psychiatric disorders, which are complex conditions influenced not only by many genes but also environmental exposure.
They exert their effects mainly by inhibiting the mevalonate pathway but also by modulating the expression of many genes not only in osteoclasts but also in cancer cells.
Many genes were only methylated in embryo but not in endosperm and many genes are more methylated in embryo than endosperm (all DMRs that the gene contained is up-regulated in embryo than in endosperm).
In fact, mRNA levels were nearly the same for many genes because only 92 of 28000 genes were differentially expressed between GDRs before and after ovulation, of which only 7 really corresponded to the oocyte genes.
2 Of the many genes affected, only 125 or so 'driver' genes seem important to tumour growth.
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