Sentence examples for many genes making from inspiring English sources

With the exception of point mutations, these lesions are rarely focal and often encompass many genes making the identification of the deregulated gene within the rearranged region problematic.

Through these ERE-independent pathways, ERs can control the expression of many genes, making them estrogen-responsive, but without involvement of the full ERE.

When expression changes due to MeCP2 inactivation have been studied previously, small expression changes have been observed on many genes making it hard to find bona fide targets of MeCP2.

In addition, the abundance of information about variability of many genes makes it possible to analyze not only single genes, but also sets of functionally related genes.

This is partly because IFN induces the expression of many effector genes, making the system rather complicated to dissect.

We have shown that many of the genes making up the inflammatory region of the eutherian MHC have been clustered for at least 350 million years.

Some amplicons and deletions span megabases and contain many genes, thus making cancer gene identification difficult.

A feature of miRNAs is that they can modulate the expression of many genes simultaneously, making them powerful post-transcriptional regulators.

The seven types of gene similarity data, including gene expression, gene ontology, pathway membership, protein sequence, protein domain, protein-protein interaction and regulation pattern, cover as many as 20,327 human genes, making the whole-genome scan of causative genes for a query disease possible.

"There were probably small changes in many genes which makes it much more difficult to pin down".

The iterative optimization process effectively removed many genes that made no or negative contribution to the classification performance.