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Sp1 is a ubiquitously expressed transcription factor and is essential for the basal transcription of many genes containing the Sp1 binding site(s).
Notably, many genes containing shifted nucleosomes were not particularly differently expressed between the strains.
Furthermore, there are many genes containing more than one region that is alternatively spliced.
In fact, postnatal downregulation of gene expression has been reported for many genes containing CpG promoters (Numata et al., 2012).
Non-sense SNVs accumulate preferentially in the 3′ end of the coding sequence (Additional file 3), suggesting that many genes containing non-sense SNVs might still be functional.
This suggests, in the same way as for SNVs, that many genes containing disruptive small InDels might still be able to keep their functionality.
Similar(46)
Many genes contain intronic regulatory sequences that are important for gene expression [34], [35].
It has been shown that many genes contain both U2- and U12-introns.
Many genes contained three base-pair indels with apparent phylogenetic signal.
The mRNAs of many genes contain two or more pair sites for miR-1273g-3p miR-1273f273f.
Many genes contained multiple significant sites, with an average of 4.7 CpGs per gene and a maximum of 114 CpGs.
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