Sentence examples for many functional elements from inspiring English sources

Non protein coding DNA contains many functional elements with influence on gene expression and regulation e.g. RNA coding sequences, transcription factor binding sides, regions of modification or with influence on chromatin (the DNA, RNA and proteins that chromosomes are made of) structure and other interacting regions [88].

Many functional elements, including TFBSs, are conserved across species [18], [19], but the proportion of TFBS conservation that can be identified directly from genome alignments is still unknown.

In pathways upregulated in the T-ALL, many functional elements depend directly or indirectly on the Ca2+ signaling.

Sequence reads also appear to be distributed throughout the genome, allowing for partial coverage of many functional elements and hundreds of orthologs of known genes.

Furthermore, there is still no clear estimate of how many functional elements are present in the genome, although it is expected that a large fraction of non-coding sequences (the vast majority of the genome) will contain such elements.

Topological domains have since been incorporated into many subsequent analyses [ 7- 9] due to the fact that they are persistent across cell types, conserved across species, and serve as a skeleton for the placement of many functional elements of the genome [ 10, 11].

But because McGovern believes modern luxury car buyers are intrigued by the structural beauty of manufactured products, the braces that hold those seats in place as well as many other functional elements of the MK 9 remain exposed and visible to the passengers.

The identification of many functional conserved noncoding elements in amphioxus [ 29] thanks to conserved synteny is thus particularly interesting, since these elements are not found in other basal chordates, whereas they are highly duplicated in vertebrates.

Many experimentally verified functional elements, such as vista enhancer elements and transcription factor ChIP sequences, have been reported for human.

The method presented here should allow the detection of many of these functional elements, which we call coding regions under non-coding selection (CRUNCS).

However, this (nearly) neutral background of intron evolution does not rule out the possibilities that, first, the very presence of introns affects the regulation of expression of the respective genes (presumably through the interaction with the splicing machinery) and hence their function, and second, that many introns harbor specific functional elements.