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As it has been suspected that genes in multicellular organisms have too many expression constraints to achieve an analog codon choice pattern for the whole genome or for most of the expressed genes [ 17], we hypothesize that translational selection is more pronounced in human genes that are expressed ubiquitously and consistently in most or all tissues.
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It was one of his many expressions.
Many constraints have efficient constraint-specific propagation algorithms.
Mr. Xi will face many constraints.
Mr. Sarkozy will face many constraints on macroeconomic coordination.
"Doctrinal Problems"* It may seem odd that we see so many constraints on expression in traditional public forums in light of today's generally permissive First Amendment landscape.
While single locus disruptions can enable the over-expression of a membrane protein, our results emphasized that there are many constraints which dictate membrane protein expression, and a universal locus that is equally effective for all membrane protein expression needs is unlikely.
The widespread social reluctance to address the issue is reinforced by many legal constraints.
There's so many design constraints".
Yet although this was a time of "opening up," many constraints remained on freedom of expression.
Coding regions that are broadly expressed face many, sometimes contradictory, evolutionary constraints on gene expression evolution [ 40], and it may be that genes with extensive expression throughout an organism are less able to evolve sex-biased expression patterns without disrupting critical functions in other tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com