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SH3 domains are protein modules that mediate protein-protein interactions in many eukaryotic signal transduction pathways.
Many eukaryotic signal transduction proteins have component-based architectures: they are built from combinations of protein interaction domains and catalytic domains.
Rho proteins function as molecular switches in many eukaryotic signal transduction pathways and, most importantly, regulate the actin cytoskeleton.
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G proteins are key components in many eukaryotic signalling pathways.
This protein comprises a family of highly conserved proteins with central roles in many eukaryotic signaling networks (Fig. 6).
The PB1 domains are present in many eukaryotic cytoplasmic signaling proteins.
The MAPK signaling proteins are involved in many eukaryotic cellular processes and signaling networks.
Whereas many eukaryotic genomes contain visible and even strong signals for periodic distribution of dinucleotides, the human genome is rather featureless in this respect.
Many eukaryotic proteins can be phosphorylated in essential cellular processes, such as signaling.
This mechanism of signaling is a conserved, ubiquitous regulatory process for many eukaryotic and prokaryotic cellular pathways (Cohen, 2000).
Protein tyrosine phosphatases (PTP) are crucial elements in eukaryotic signal transduction.
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