Sentence examples for many epigenetic marks from inspiring English sources

In addition, a recent report suggests that many epigenetic marks remain unknown and are still to be explored (Tan et al. 2011).

DNA methylation, like many epigenetic marks, may be heritable, therefore unintended changes as a result of environmental exposures or other processes can be passed on for multiple generations [ 11].

Our observations now link many important epigenetic marks to cell cycle and transcriptional transitions that occur at the mid-blastula transition and the onset of zygotic transcription.

Many other epigenetic marks, along with their aberrant levels that potentially trigger or anticipate disease states, are expected to be identified in the foreseeable future [ 18], with the International Human Epigenome Consortium aiming to go far beyond the Roadmap Epigenomics Consortium, up to more than 1000 human reference epigenomes [ 3].

ChIP-seq data is being rapidly generated not only for many TFs and epigenetic marks, but also in multiple conditions, tissues, cell types, and individuals.

While many of these epigenetic marks, like DNAm, correlate closely with the transcriptional status of a single promoter, there are also long-range interactions that impact gene expression.

DNA enrichment methods are widely used for genome-wide identification of many different kinds of epigenetic marks.

In particular, given the growing evidence for the dynamic nature of epigenetic marks at many sites and the need for active maintenance of these marks at many sites [ 39], these sets of differences may be actively maintained in each cell type.

Further resetting of epigenetic marks accompanies differentiation of many specialized cell types of the body as well as placenta and other transient structures during pregnancy, and subsequent development of body structures during various postnatal stages of development.

These findings raise the possibility that several euchromatin-associated epigenetic marks are elevated in many genes of the intestine on fasting regardless of whether the transcript amounts decrease or not.

These centers display specific and robust epigenetic marks, which are maintained through many cell cycles [18].