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Its R-enantiomer is an essential cofactor for many enzyme complexes.
Furthermore, homologous sequences of cyt b can be found in many enzyme complexes with quinol oxidase activity, such as the cytochrome b6 f (cyt b6 f) complexes from Cyanobacteria and chloroplasts (Kurisu et al. 2003; Stroebel et al. 2003) or the Sulfolobales quinone oxidase (Sox) complex from thermoacidophilic Archaea (Schäfer et al. 2001).
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A general understanding of such electrostatic effects is important given the generally large impact salt concentration has on the kinetic and thermodynamic properties of many enzyme-DNA complexes.
Hence, as noted with many enzyme-ligand complexes, the Δ C p ° values for the binding of the SAHA analogues to HDAC8 cannot be rationalized solely in light of the classical hydrophobic model (see Discussion).
Many aromatic polyketides are synthesized by bacterial enzyme complexes called polyketide synthases (PKSs).
CS/DS expression is controlled by many enzymes in a complex biosynthetic pathway and this leads to considerable variation in structure and function.
Along with the frequent differences in enzyme modular structures noted above, this suggests that there may be many differences in the detailed organization of the cellulolytic enzyme complexes between the two strains.
Many important antibiotics, siderophores and toxins are synthesized on NRPS enzyme complexes [ 16].
Large molecular machines perform many cellular processes and it is of fundamental interest to understand how these enzyme complexes work in detail.
Many important antibiotics, antimicrobial compounds, siderophores and toxins are synthesized on non-ribosomal peptide synthetase enzyme complexes [ 16].
Fig. 10 Illustration of different modes of organizing enzyme complexes.
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