Although many endpoints were tested in our injury model, gastric score, MPO activity and MDA quantity are the best.
Many endpoints have been measured in bystander cells, including sister chromatid exchanges, micronuclei, apoptosis, terminal differentiation, mutation and gene expression changes [ 5- 9].
Many endpoints have been reported for the bystander responses, including DNA damage markers [ 11, 12] cell death [ 13], increases in sister chromatid exchanges [ 14, 15], micronuclei [ 11, 16, 17], mutations [ 18, 19] genomic instability [ 20, 21], malignant transformation [ 22, 23] and gene expression [ 24].
Despite widespread use in clinical trials, many intermediate endpoints are poorly defined or have varying definitions in the literature, making it difficult to consistently interpret treatment effects and reliably perform cross-trial comparisons.
Although many of these endpoints are difficult to quantify, they clearly represent ancillary benefits of energy savings.
In many experiments in the life sciences, several endpoints are recorded per subject.
Evidence demonstrates these compounds to be capable of influencing the behaviour of fish, but the relevance of many reported behavioural endpoints is unclear and the value of some findings has been questioned.
The API returns JSON and all of the RESTful endpoints are described here.
"Surrogate endpoints are not working".
