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Many effects due to the stochastic nature of the problem have been detected.
The use of an input function for quantitation of biological function seeks to reduce many effects due to systemic variations.
As with cetuximab, it is entirely possible that JAK1i creates many effects (due to altered signaling of several pathways) that are involved in radiosensitivity, but our results suggest that greater slowing of the repair of radiation-induced DNA dsbs contributes to the JAK1i - mediated enhancement of cetuximab-induced radiosensitization.
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The physics of the gain medium is analyzed with an emphasis on the role of many-body effects due to the Coulomb interaction of the carriers for the optical properties of the active semiconductor material.
Taken within the context of our previous finding that TREM-2 recruitment on DCXAb mediates the induction of antigen accumulation by mature DC [3], we conclude that B7-DC XAb has its many unique biologic effects due to its ability to specifically target the surface of DC, recruit, and activate common signaling pathways in DC that, in turn, modulate multiple T cell functions.
It should be noted that the water management is influenced by many effects, e.g., water removal due to high reactant flow rate [25] or GDL oxidation by substances as hydrogen peroxide and sulfuric acid degrades fuel cell operation [16, 26].
Our research programme on fee exemption policies in Burkina Faso, Mali and Niger has revealed many shortcomings, bottlenecks, and unexpected effects due to the implementation process of these policies [ 1].
26 In addition, many drugs differ in their effects due to ethnic and cultural diversity: β-blockers and ACE inhibitors in hypertension are commonly recognised examples, yet there are certainly many others.
Our results suggest that many effects of amphiphilic phytochemicals are due to cell membrane perturbations, rather than specific protein binding.
However, when effective population sizes remain moderate, inbreeding over many generations may have marked fitness effects due to increasing disease susceptibility and inbreeding depression [ 2, 6- 8].
The human populations around the globe have faced many problems and also harmful health effects due to the residual effects of synthetic pesticides.
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CEO of Professional Science Editing for Scientists @ prosciediting.com