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There are many drug classes that may be used to treat depression, including the selective serotonin-reuptake inhibitors (SSRIs) citalopram (Celexa®) and sertraline (Zoloft®), as well as the aminoketone bupropion (Wellbutrin®).
With many drug classes available, translational studies are needed to identify the most effective, safe, and simplest antidiabetes treatment sequences.
This organism is uniquely problematic because of a combination of inherent resistance to many drug classes and its ability to acquire resistance to all relevant treatments [ 3].
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Time-series analysis showed that %MRSA had a relationship with the use of many antimicrobial drug classes.
The strains harboring NDM are broadly resistant to many other drug classes in addition to β-lactams and carry a diversity of other resistance mechanisms, which leaves few treatment options (tigecycline or colistin) [ 63, 64].
Although it would be of interest to perform separate regressions for each class of antibiotic to see if the correlation holds across different mechanisms of action, for many of the drug classes, sample sizes are too small to permit reliable regression coefficients to be estimated.
The pharmacophore, which contains two hydrogen bond acceptors (lipid) and two hydrophobic (aromatic) features, was found to map well onto many well-known antimalarial drug classes including quinolines, chalcones, rhodamine dyes, Pfmrk cyclin dependent kinase inhibitors, malarial FabH inhibitors, and plasmepsin inhibitors.
Since then many new compounds and drug classes for the treatment of HIV infection have been developed that have substantially increased the complexity of HIV patient care [4].
How many drugs or "therapeutic classes" must be covered by a prescription-drug plan starting in January 2006?
However, many examples from a range of drug classes have been published of over/underconcentration of APIs in marketed drugs (see Table 1 11– 39).
The triazoles are the most widely used antifungal agents and have activity against many fungal pathogens, with less serious nephrotoxic effects observed than with amphotericin B. However, the azoles antifungals have many drug-drug interactions with multiple drug classes owing to their interference with hepatic cytochrome P-450 enzymes [ 6].
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CEO of Professional Science Editing for Scientists @ prosciediting.com