Sentence examples for many downstream proteins from inspiring English sources

As expected, EGFR and many downstream proteins in the pathway are differentially phosphorylated in NSCLC samples.

Several pathways, involving many downstream proteins, mediate the effects of TGF- β1.

Our results suggested many downstream proteins of BR signaling are induced by phosphorylation via various kinases, not through transcriptional regulation.

Exposure to ROS leads to reversible oxidation of thiol groups of key cysteine residues in many downstream proteins, including transcriptional regulators, kinases, Rho and RAS GTPases, phosphatases, structural proteins, metabolic enzymes, and SUMO ligases.

One of the main target of FAK-Src activation is p130Cas [ 15] that behaves as a scaffolding protein and recruits many downstream signaling proteins such as Rap1 and Rac [ 16].

Overexpression of Vav proteins enhances lamellipodium and ruffle formation, migration, and cell spreading, and augments activation of many downstream signaling proteins like Rac, ERK and Akt.

Many downstream target proteins are then activated through Akt- and GSK-3 β-mediated phosphorylation.

PTEN has a dual phosphatase activity that regulates AKT and many downstream signaling proteins [ 27].

Similarly MAPKs are also contain short docking site that recognizes many downstream target proteins by utilizing the same strategy.

In contrast to many other studies (e.g., 50), our proteomic approach was designed not to detect ROS or RNS but to detect many downstream regulated proteins, providing a new perspective on plasma treatment effects.

T-oligo/WRN interaction results in formation of DNA γH2AX damage-like foci at the telomeres [ 25] with activation of ATM [ 8, 32] and its many downstream effector proteins, leading to apoptosis and senescence [ 5, 7, 8, 32].