Sentence examples for many downstream pathways from inspiring English sources

Indeed, many downstream pathways appeared to be specifically activated after cluster thinning.

Such compounds alter the epigenetic landscape and may impact many downstream pathways simultaneously.

One of the many downstream pathways from CaMKII is the Ras Raf mitogen-activated pRas Raf mitogen-activated(MEK)–ERK (Ras-Raf-MEK-ERK) signalling protein.

IRS-1 phosphorylation results in the activation of many downstream signaling pathways; many of these pathways are implicated in mitogenesis and protection from apoptosis.

EGFR stimulation activates many downstream signaling pathways including the PI3K/Akt pathway [9].

Activated TβRI interacts with and phosphorylates a number of proteins, thereby activating many downstream signaling pathways, including the Smad (Sma/Mothers Against Decapentaplegic) pathway.

Another consideration is that while PI3Ks are important regulators of Foxo transcription factors, many downstream signaling pathways controlled by PI3Ks regulate post-transcriptional, metabolic, cytoskeletal and other relevant cellular events [41].

B-Raf, the protein product of BRAF, is a serine/threonine protein kinase and the first in the mitogen-activated protein kinase (MAPK) cascade which is one of the many downstream effector pathways of Ras.

Importantly, elevated KRAS activity stimulates many downstream signaling pathways.

Activation of the TLR2-MyD88-IRAK1-TRAF6 can lead thethe activation of many downstream signaling pathways, including members of the mitogen-activated protein kinase (MAPK) family [ 19, 35].

Ras is a small GTPase that connects RTK activation to the triggering of many downstream effector pathways including MAP kinase cascades.