At least 10 distinct genetic syndromes are strongly associated with HSCR, and many other disorders affecting genes without a clear role in ENS development occasionally include HSCR.
Secondly, many psychiatric disorders affect abilities related to decision making, which means that psychiatrists often meet patients with impaired decision-making capacity.
In transmissible spongiform encephalopathies (TSEs), a group of fatal neurodegenerative disorders affecting many species, the key event in disease pathogenesis is the accumulation of an abnormal conformational isoform (PrPSc) of the host-encoded cellular prion protein (PrPC).
In more severe forms of the CDG characterized by multisystem disorders affecting many organs, hypotonia is a frequent feature.
In the attempt to shed light on the contribution of GAS infections to the onset of neuropsychiatric or behavioral disorders affecting as many as 3% of children and adolescents, we tested the antibody response of tic patient sera to a representative panel of GAS antigens.
In hand surgery trials, it is often possible to take several measurements from the same patient, because many disorders here affect bilateral or multiple structures, such as the hand itself, the finger joints or the tendons.
Age-related macular degeneration (ARMD), unlike many other retinal disorders, affects central vision and spares peripheral vision.
Many of these disorders affect the lungs, either exclusively or as part of a systemic syndrome.
"Memory disorders affect many people who never played football or other sports," Mr. Aiello said.
When the league-sponsored Michigan study reported this September that retirees were reporting rates of Alzheimer's and other memory-related diseases at five times or more the national rate, Aiello said, "There are thousands of retired players who do not have memory problems," and, "Memory disorders affect many people who never played football or other sports".
