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However, the lack of lipid droplet in many differentiating cells suggests adipogenic gene expression is insufficient for lipid droplet formation.
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However, surprisingly many of the differentiating cells under these conditions flattened and evolved into a shape similar to smooth muscle cells (Fig. 3C, D; black arrows).
Most cancer therapies target differentiated or differentiating cells, regardless of whether or not they are cancerous.
The antioxidant vitamin E also protected both undifferentiated and differentiating cells from many of the adverse effects of CPF but worsened the impact on AC signaling.
The third treatment, the antioxidant vitamin E, also protected both undifferentiated and differentiating cells from many of the adverse effects of chlorpyrifos, but worsened the deterioration of adenylyl cyclase signaling.
They unambiguously demonstrate that cell cycle progression coexists with terminal differentiation, thus explaining how differentiating cells increase in size.
Supplementary Figure 3 Representative phase contrast images of differentiating cells at different time points of EN induction.
Through this mechanism, a stem cell can produce both self-renewing and differentiating cells in a single cell division.
Through this mechanism, stem cells achieve the production of both self-renewing and differentiating cells in a single cell division.
This suggests that eventually most differentiating cells become polyploid.
Expression of neuronal marker genes in the differentiating cells was analyzed by RT-PCR (Figure 6B).
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