Sentence examples for many different peptides from inspiring English sources

This leads to the possibility that many different peptides or small molecules might be labeled and purified in a similar manner with subtle changes to achieve optimum yields.

This is of interest as many different peptides have been implicated in chronic responses to ethanol in mammals including NPY [41], CRF [30] and the opioid peptides [42], [43].

The assays used for this publication required only 25 μL of sample yet were able to identify many different peptides.

As expected, abundant proteins were associated with many different peptides: vimentin, 23 peptides; HSP90β, 20 peptides; and β-actin, 14 peptides.

Last, the entire process can be performed in parallel, which makes it possible to simultaneously analyze the binding properties of many different peptides.

Here, we used another approach to analyze specificity and effector function (overlapping peptide libraries and intracytoplasmic IFN-γ staining), with the intention being to demonstrate priming to many different peptides derived from the same tumor antigen.

Such cumbersome production protocols have limited dissemination and restricted availability of peptide-MHC tetramers effectively precluding large-scale screening strategies involving many different peptide-MHC tetramers.

It is simple, robust, and versatile technique with a very broad application potential as it can be adapted both to small- and large-scale production of one or many different peptide-MHC tetramers for T cell isolation, or epitope screening.

It is not a simple task since the genes encoding HLA proteins are extremely polymorphic giving rise to many different peptide binding specificities being expressed in the human population.

As the HLA class II molecules presenting the hTERT epitope to the T-cell clones were different (−DQ, −DR, and −DP) and the three clones have different fine-specificity (results not shown), these results strongly suggest that natural processing of hTERT may give rise to many different peptide fragments, fitting into multiple HLA class II molecules.

Given that a single T-cell receptor (TCR) can in principle see many different peptide-MHC class I complexes (Sewell, 2012; Wooldridge et al., 2012), the two MHC specific chaperones of the MHC class I antigen presentation pathway, may be the crucial influence in selecting immune responses.