Sentence examples for many different extracellular from inspiring English sources

Apparently, collagen III is not fully representative for interstitial fibrosis, which is a reflection of interstitial matrix accumulation of many different extracellular matrix molecules.

MAPK activation may be secondary to many different extracellular stimuli, but the series of phosphorylation cascade activation events are critical to the responses.

40 Given the ubiquitous importance of these signal-transduction molecules in the response of all cells to many different extracellular signals, it is questionable whether these agents will have sufficient specificity.

Since it has been well validated that miR-29 functions through the regulation of many different extracellular matrix related genes (van Rooij & Olson, 2012), we confirmed the regulation of a subset of these target genes.

OPC migration is not only controlled by secreted molecules, but is also regulated by contact-mediated mechanisms involving many different extracellular matrix proteins and cell surface molecules [ 52, 88, 199], N-cadherins [ 125, 133, 145, 167, 190], and possibly even additional, yet unidentified molecules.

Gelatinases cleave many different targets (extracellular matrix, cytokines, growth factors, chemokines and cytokine/growth factor receptors) that in turn regulate key signaling pathways in cell growth, migration, invasion, inflammation and angiogenesis.

After a widespread observation of many different kinds of extracellular vesicles, emerging from quite different fields of biology and medicine, the modern puzzling questions deal about the life functions of these vesicles.

uPA converts plasminogen into the active serine protease plasmin, a broad spectrum protease that can degrade many different types of extracellular matrix proteins in addition to activate latent growth factors and matrix metalloproteases [ 24, 25].

The distribution of annotations to terms in the subontology cellular component shows that the gene products corresponding to the ESTs identified in this work are active in many different cellular and extracellular locations.

Such a degradation requires the concerted action of proteases which are involved in the proteolysis of many different components of the extracellular matrix [ 24].

Upon activation, cells of many different lineages bud small extracellular vesicles called microparticles (MP) (also known as microvesicles or ectosomes) from the cytoplasmic membrane.