Sentence examples for many different conformations from inspiring English sources
Intrinsically disordered proteins (IDPs) are characterized by highly flexible solvent exposed backbones and can sample many different conformations.
In protein redesign one of the main challenges is the ability to evaluate many different conformations of the redesigned protein in order to determine the best structure.
Many recently discovered noncoding RNAs do not fold into a single native conformation but sample many different conformations along their free-energy landscape to carry out their biological function.
EM images of negatively stained samples of a Dscam construct containing eight of the Ig-like domains showed it to be very flexible and to adopt many different conformations [13].
The 20 available NMR structures of RRM1 of SF2/ASF [64] when viewed collectively hint that the N-terminal extension is probably flexible and can adopt many different conformations, such that this region could sometimes occlude key RNA-binding residues on the protein's β-sheet.
Large parts of the surface are relatively flat, which means that in these areas the peptide can exist in many different conformations with essentially equal probability.
In reality, however, domain-peptide complexes exist in many different conformational states, dynamically moving from one conformation to another.
In addition, the conformation of an oligomer state of specific order (for example, dimers) also is populated by many different conformers.
In most of the above examples, genotype determines the likelihood, but not the certainty, of particular epitypes and phenotypes being displayed, because the same DNA sequence may be flexibly reprogrammed into many different chromatin conformations.
Usually many different alternative conformations that fit the stem residues are selected and sorted according to geometric criteria or to the sequence similarity between the template and target loop sequences.
At pH 6, where this antiporter is fully active, the helices involved in ion translocation appear disordered, due to averaging over many slightly different conformations on the crystal lattice.
