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Once a tool has been adapted to UIMA, it can be used in many different assemblies or pipelines with other tools also adapted to UIMA.
Together, the data support a model whereby the plant polyadenylation complex consists of a relatively constant core and numerous combinations of peripheral subunits, such that the complex as a whole is actually a population of many different assemblies, which might explain the highly degenerate nature of the plant poly(A) signals.
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By checking how often these agreed, she could approximate the mathematical "entropy" of the system a measure of how disordered it was.A complicated factory, with many different assembly lines, can still be ordered if everything is proceeding according to plan.
While many different assembly strategies combining different tools have been tested in previous transcriptome studies [ 42], we chose to use the MIRA assembler, which was present in the top three assemblers used in recent 454 transcriptome projects [ 43] and has proven to work well on pea [ 16] and on other complex species like rapeseed [ 20] or wheat [ 44].
In order to analyze the assembly quality of many different assemblers and to understand the inconsistency of many traditional metrics, it was decided to collect a significant volume of comparative performance statistics using a large benchmark of both bacterial and human genome data.
FA formation and dynamics are challenging subjects to investigate because many different molecular assemblies of proteins are formed that are difficult to dissect.
The sprawling, two-story white building houses many different short assembly lines.
Recent structure studies have demonstrated the presence of many different conformational assembly states of the Mediator complex (Tsai et al. 2014; Wang et al. 2014), indicating the intrinsic flexibility and heterogeneity.
Thirdly, as many different array designs and genome assemblies exist, the results from different groups could be difficult to compare.
This required a huge effort of software assembly, using many different modeling approaches and countless hours of manual data mining.
Here, we show the dynamic nature of IS 6100-mediated pathway assembly, with many different insertion sites around the lin genes.
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