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If epigenetic pathways are blocked, often many developmental aberrations arise resulting in a complex phenotype.
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Loss of the piRNA pathway leads to derepression of many TEs and results in DNA damage and developmental aberrations.
This can be put down to the fact that many protocols are inadequately reproducible, a differing fraction of the embryos shows developmental aberrations and non-embryogenic callus frequently arises during the use of indirect embryogenesis systems.
However, unexpected and prominent developmental aberrations resembling those described for mutants defective in brassinosteroid signaling were observed in many of the lines.
Sox9 regulates many developmental processes.
There are many programs claiming many developmental benefits, but few real gems on the market.
I have been able to initiate many developmental changes in my village in the last five years.
Studying patients from three unrelated pedigrees characterized by neutropenia, specific granule deficiency, myelodysplasia with excess of blast cells, and various developmental aberrations, we identified three homozygous loss-of-function mutations in SMARCD2.
Ms. Worobey points out that cooking also helps children achieve many developmental milestones.
Lipomas are considered to be rare congenital benign malformations resulting from developmental aberrations involving the meninx primitiva.
Foregut budding error may lead to bronchogenic cyst, esophageal duplication cyst, or "bronchopulmonary foregut malformations" (BPFM), a term proposed in 1968 by Gerle et al. [5] to encompass the full spectrum of developmental aberrations of the embryonic foregut.
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