The MYC oncoprotein is involved in many critical processes in malignant cells, including proliferation, growth, differentiation, and metabolism [26].
Endothelial intercellular junctions play an essential role in many critical processes, including survival, angiogenesis and inflammation [ 1- 3].
Many critical processes occurring during peri-natal immune development are either nonexistent or comparatively unimportant in the adult (e.g., Table 1).
The importance of glutamine for many critical processes in cancer cells and the fact that glutamine metabolism is regulated by both oncogenes and tumor suppressors [ 29– 31] makes this branch of cancer metabolism another attractive target for therapeutic strategies, in particular involving mitochondrial activity, glutamine being a high-energy mitochondrial fuel.
This phenomenon is essential for life and underlies many critical homeostatic processes in cells.
Dear Editor, In eukaryotic cells, the endoplasmic reticulum (ER) is a continuous membrane system involved in many critical cellular processes, including protein synthesis, lipid synthesis, and calcium storage.
A special class of these models, called landscape models (LMs), simulates dynamics at intermediate scales where many critical ecosystem processes interact.
The phospholipase-catalyzed release of free fatty acids (FFAs) from phospholipids is implicated in many critical biological processes such as neurotransmission, inflammation, and cancer.
In doing so, miRNAs regulate many critical developmental processes, including cellular proliferation, differentiation, migration, and apoptosis, as well as more specialized biological functions such as dendritic spine development and synaptogenesis.
Ubiquitination controls many critical cellular processes, most of which require specific lysines on ubiquitin (Ub).
