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Many conventional cell lysis approaches including chemical, electrical, thermal, optical, and acoustic methods need multiple steps that affect the integrity of extracted proteins and nucleic acids.
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The lymphoma cells, although lacking many conventional B-cell markers, carry immunoglobulin gene rearrangement and express syndecans, suggesting pre-plasma cell origin.
Since cancer is characterized by runaway growth of cells, many conventional chemotherapy drugs disrupt cell growth.
Many conventional anticancer treatments kill cells irrespective of whether they are normal or cancerous; therefore, patients suffer adverse side effects due to healthy cell loss.
In addition, many conventional or serially transplanted GBM cell lines express cadherin 11 (Figure 2, 4), another classic EMT marker.
Actin belongs to the most abundant proteins in eukaryotic cells which harbor usually many conventional actin isoforms as well as actin-related proteins (Arps).
Many decades of heuristic optimization have gone into perfecting conventional cell culture devices and protocols.
Many conventional anticancer drugs induce ROS generation and trigger cancer cell apoptosis via ROS MAPK pathway.
Resistance of putative CSC against many conventional cancer therapies is associated with two main characteristics: 1) a slow cell division rate; and 2) the ability to efflux antitumor drugs [ 20].
The clinical implications of this hypothesis have been well recognized: many current cytotoxic therapies (including radiotherapy and many conventional chemotherapeutic agents, such as spindle poisons) are based on killing rapidly dividing cells.
Unlike many other viruses, the concept of "strain" is not used for papil-lomaviruses as they cannot be grown by conventional cell culture methods.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com