Sentence examples for many control regions from inspiring English sources

These binding sites are present in many control regions of both tissue-specific and ubiquitously expressed genes [ 6, 7] indicating that Sp-family transcription factors potentially regulate a large number of target genes.

Indeed many control-region data from the literature, if compared to the mtDNA sequences of the present study can now be classified into known haplogroups.

A key issue in generating reporter gene fusions is that, in order to accurately reflect all aspects of the temporal and spatial pattern of expression of the gene of interest, as many cis-regulatory control regions as possible need to be included in the DNA construct.

Analysis can simultaneously include coding and control regions, many samples can be studied in parallel, and even minor heteroplasmic changes can be detected.

No CSB has been found among the control regions and many parts of the control regions do not appear to be particularly important for regulatory functions.

To achieve effective control of gene expression in vivo, higher eukaryotes generally utilize extensive promoter/enhancer/locus control regions spanning many kilobases of DNA, and encompass multiple discrete binding sites for transcription factors that combinatorially encode specificity of gene transcription.

In many imprinted gene clusters, imprint control regions (ICRs) function as discrete cis-acting DNA elements that are characterized by heritable epigenetic marks that distinguish the two parental alleles [ 16].

Researchers' ignorance of these control regions and what many of them do might doom the effort.

In fetal PSGs, the de novo DNA methyltransferase DNMT3A and its cofactor DNMT3L are expressed highly, and paternally methylated imprinting control regions (ICRs) and many retrotransposons are methylated de novo [ 17– 17].

Third, although many studies have investigated concerted evolution of mitochondrial control regions, few have investigated evolution of duplicated regions adjacent to the control region.

imprinting control regions.