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To the contrary, evidence from model organisms suggests that HGIs frequently influence genetic studies and contribute to many complex traits.
Jointly modeling multiple traits' genetic profiles has provided insights into the shared genetic basis of many complex traits.
For many complex traits, the bulk of the phenotypic variation attributable to genetic factors remains unexplained, even after well-powered genome-wide association studies.
Exploring gene-gene interactions may provide additional insights into many complex traits when explored in properly designed and powered association studies.
GWAS offer a hypothesis-free alternative to candidate gene studies and have recently brought novel insights into the biological and genetic underpinnings of many complex traits, including migraine [24].
These include the generation of a highly resolved family tree of extant species, genome-wide association studies across species to identify genetic substrates of many complex traits, redefinition of species and the species concept, reconstruction of the genomes of common ancestors, and generation of new computational tools to address these questions.
Similar(18)
To assume that many complex adult traits are determined at birth is "so last century".
"Many complex human traits have their roots in fundamental brain processes that are shared among many other species.
Darwin believed, as do biologists today, that natural selection can explain the origin of many complex adaptive traits.
As well as conferring susceptibility to recessive Mendelian diseases, ROH are also potentially an underappreciated risk factor for common complex diseases, given the evidence for a recessive component in many complex disease traits [18]; they will allow quantification of the risk arising from recessive genetic variants in different populations.
Studies of de novo genomic variation have not yet been performed for many complex human traits.
More suggestions(15)
many complex variations
diverse complex traits
many complex requirements
many complex networks
many complex situations
many accessible traits
many complex people
many complex ions
many complex tasks
many complex exercises
many complex challenges
many other traits
many complex structures
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many complex problems
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